Difference between revisions of "MutM"
| Line 78: | Line 78: | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2F5S 2F5S] (complex with oxoG:C, Geobacillus stearothermophilus) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2F5S 2F5S] (complex with oxoG:C, Geobacillus stearothermophilus) | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34403 O34403] |
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU29080] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU29080] | ||
Revision as of 14:04, 20 July 2009
- Description: formamidopyrimidine-DNA glycosidase
| Gene name | mutM |
| Synonyms | ytaE |
| Essential | no |
| Product | formamidopyrimidine-DNA glycosidase |
| Function | DNA repair |
| MW, pI | 31 kDa, 8.889 |
| Gene length, protein length | 834 bp, 278 aa |
| Immediate neighbours | ytaF, polA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29080
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine (according to Swiss-Prot)
- Protein family: FPG family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2F5S (complex with oxoG:C, Geobacillus stearothermophilus)
- UniProt: O34403
- KEGG entry: [2]
- E.C. number: 3.2.2.23
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
