yybM

yybM
168

unknown

Locus
BSU_40590
Molecular weight
28.97 kDa
Isoelectric point
8.32
Protein length
251 aaSequenceBlast
Gene length
756 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
yybM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms

This gene is a member of the following regulons

Rok regulon, DnaA regulon

Gene
Coordinates
4,173,665 → 4,174,420
The protein
Structure
P37491 (AlphaFold)
Expression and Regulation
Operons
Genes
yybN-yybM-yybL-yybK-yybJ
Description
PubMed
Regulation
repressed by Rok-DnaA PubMed
Regulatory mechanism
Rok: repression, Rok-DnaA PubMed, in rok regulon
DnaA: repression, Rok-DnaA PubMed, in dnaA regulon
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yybN→yybJ

2025-03-10 21:55:35

Jstuelk

67

7269b326596a2b101b6906259d47b3c6c5f251ce

5AE2E862BF55A5CF21A83C6468D64DAD9CCB6367

Biological materials
Mutant
MGNA-B841 (yybM::erm), available at the NBRP B. subtilis, Japan
BKE40590 (ΔyybM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTCTCACTCAATTCTT,  downstream forward: _UP4_ACAATGAAAATTAAAAGACT
BKK40590 (ΔyybM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTCTCACTCAATTCTT,  downstream forward: _UP4_ACAATGAAAATTAAAAGACT
References
Seid CA, Smith JL, Grossman AD Genetic and biochemical interactions between the bacterial replication initiator DnaA and the nucleoid-associated protein Rok in Bacillus subtilis. Molecular microbiology. 2017 Mar; 103(5):798-817. doi:10.1111/mmi.13590. PMID:27902860
Salzberg LI, Powell L, Hokamp K, Botella E, Noone D, Devine KM The WalRK (YycFG) and σ(I) RsgI regulators cooperate to control CwlO and LytE expression in exponentially growing and stressed Bacillus subtilis cells. Molecular microbiology. 2013 Jan; 87(1):180-95. doi:10.1111/mmi.12092. PMID:23199363
Albano M, Smits WK, Ho LT, Kraigher B, Mandic-Mulec I, Kuipers OP, Dubnau D The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions. Journal of bacteriology. 2005 Mar; 187(6):2010-9. . PMID:15743949

BA4CB875FD72C7E7767AFA44A5D8C32448F5E18C

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Time of last update: 2025-04-04 02:48:51

Author of last update: Bzhu