spoIIT

spoIIT
168

co-activator (with SpoIIR) for triggering SpoIIGA-dependent processing of SigE

Locus
BSU_36770
Molecular weight
28.48 kDa
Isoelectric point
6.88
Protein length
Gene length
Function
control of SigE processing and activation
Product
co-activator (with SpoIIR) for triggering SpoIIGA-dependent processing of SigE
Essential
no
Synonyms
spoIIT, ywmB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

SigA regulon, SigF regulon

Gene
Coordinates
3,779,293  3,780,033
Phenotypes of a mutant
mild sporulation defect due to inefficient activation of SigE PubMed
inactivation of ''spoIIT'' reduces sporulation efficiency to 38% that of wild type cells; abortively disporic PubMed
The protein
Structure
secreted from the forespore to the intermembrane space between the forespore and the mother cell PubMed
Expression and Regulation
Operons
Description
Regulation
expressed early during sporulation in the forespore (SigF) PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigF: sigma factor, PubMed, in sigF regulon
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ywzBmurAA

2025-01-14 17:19:38

Bzhu

83

348b92db57f702141368550bd6f8ee854f499e36

A3D075B597018E5E660B1BB16E5A4B840E277744

Description
Regulation
expressed early during sporulation in the forespore (SigF) PubMed
Open in new tab

spoIITmurAA

2025-01-15 07:27:17

Bzhu

86

8686823a2584a3b9acd44b2f60efbd7dabdbf1a7

EC335D8C98E1864C25DE56486949E2C94D39B0B9

Biological materials
Mutant
MGNA-A189 (ywmB::erm), available at the NBRP B. subtilis, Japan
BKE36770 (spoIIT::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTTCATCTCTCCCCCTT,  downstream forward: _UP4_TAATATAGAGAATTTAGGGA
BKK36770 (spoIIT::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTTCATCTCTCCCCCTT,  downstream forward: _UP4_TAATATAGAGAATTTAGGGA
References
Reviews
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Original Publications
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3A8E0417C4EC85FDDE1178B775F6579C8F1009C6

Page visits: 2442

Time of last update: 2025-01-17 03:33:29

Author of last update: Jstuelk