yusV

yusV
168

ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin, as well as for the siderophores schizokinen and arthrobactin (ATP-binding protein)

Locus
BSU_32940
Molecular weight
30.34 kDa
Isoelectric point
5.32
Protein length
275 aaSequenceBlast
Gene length
828 bpSequenceBlast
Function
acquisition of iron
Product
ABC transporter for the siderophores Fe-enterobactin, Fe-bacillibactin, schizokinen and arthrobactin  (ATP-binding protein)
Essential
no
Synonyms
yusV
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1120 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,379,112  3,379,939
Phenotypes of a mutant
severe growth inhibition upon addition of subinhibitory concentrations of mirubactin C PubMed
The protein
Catalyzed reaction/ biological activity
ATPase for the FeuA-FeuB-FeuC siderophore ABC transporter and for the YfhA-YfiY-YfiZ siderophore ABC transporter
Protein family
ABC transporter superfamily (according to UniProt)
Domains
ABC transporter domain (aa 6-242) (according to UniProt)
Structure
4R9U (PDB), the E. coli BtuC-BtuD complex, BtuD shares 32% identity, 57% similarity with YusV, PubMed
O32188 (AlphaFold)
Paralogous protein(s)
FhuC, FecF, FpbP
Localization
associated to the membrane (via FeuB-FeuC and YfhA-YfiZ) PubMed
Expression and Regulation
Operons
Genes
yusV-yusU
Description
PubMed
Regulatory mechanism
Fur: repression, PubMed, in fur regulon
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yusV->yusU

2025-03-18 11:12:21

Bzhu

67

4e7a9dafa4f87d41b83558ecb3809bec3a77233d

17071F01FAA35B5E08D9C5FDB32CE35CDDB02F6B

Biological materials
Mutant
MGNA-B599 (yusV::erm), available at the NBRP B. subtilis, Japan
BKE32940 (yusV::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAACCGCTCCTTTTTGCT,  downstream forward: _UP4_TAAATAACGCAGCGAAGGAG
BKK32940 (yusV::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAACCGCTCCTTTTTGCT,  downstream forward: _UP4_TAAATAACGCAGCGAAGGAG
References
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Page visits: 4571

Time of last update: 2025-04-08 18:43:52

Author of last update: Jstuelk