spsD

spsD
168

legionaminic acid synthesis

Locus
BSU_37880
Molecular weight
32.99 kDa
Isoelectric point
6
Protein length
Gene length
Function
legionaminic acid synthesis
Product
unknown
Essential
no
Synonyms
spsD, ipa-66d

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1670 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,888,862  3,889,731
Phenotypes of a mutant
the mutant tends to acquire suppressor mutations that result in improved growth PubMed
less hydrophobic spore surface PubMed
The protein
Catalyzed reaction/ biological activity
required for spore crust assembly, legionaminic acid synthesis PubMed
N-acetyltransferase domain (aa 137-289) (according to UniProt)
Structure
Expression and Regulation
Operons
Description
Regulation
expressed during sporulation in the mother cell (SigE, SigK, GerE) PubMed
Regulatory mechanism
GerE: activation, PubMed, in gerE regulon
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
SigK: sigma factor, PubMed, in sigK regulon
Additional information
the mRNA is very stable (half-life > 15 min) PubMed
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spsAspsL

2025-01-23 06:36:53

ghost

124

8fd40e70daa9bc3b7d469fa252e122a98e4555de

9FCD794B68194823BCA66D7E89CC93E5AF9CC0AA

Biological materials
Mutant
BKE37880 (spsD::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_GACATTTTCTTTTACCGTAT,  downstream forward: _UP4_TGGCCGGGCAAGGAGGCGAA
BKK37880 (spsD::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_GACATTTTCTTTTACCGTAT,  downstream forward: _UP4_TGGCCGGGCAAGGAGGCGAA
References
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Time of last update: 2025-01-30 05:20:44

Author of last update: Jstuelk