psdA

psdA
168

ABC transporter (ATP-binding protein) for the export of lipid II-binding lantibiotics, such as nisin and gallidermin

Locus
BSU_34700
Molecular weight
28.89 kDa
Isoelectric point
6.34
Protein length
Gene length
Function
export of toxic peptides
Product
ABC transporter (ATP-binding protein)
Essential
no
Synonyms
psdA, yvcR

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1136 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,565,496  3,566,275
The protein
Protein family
ABC transporter superfamily (according to UniProt)
ABC transporter domain (aa 4-248) (according to UniProt)
Structure
1L2T (PDB) (MJ0796 from Methanocaldococcus jannaschii, 44% identity) PubMed
Paralogous protein(s)
membrane associated (via PsdB) PubMed
Expression and Regulation
Operons
Description
Regulation
''psdA'': induced by nisin, gallidermin (PsdR) PubMed
Regulatory mechanism
PsdR: activation, PubMed, in psdR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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psdRpsdB

2024-12-21 13:52:36

ghost

60

d7c5e7b0711e6228a3cdf2a71273ad8f725b7c09

5FD7CD564F41C61165A1333E78C1CCE35B7CF017

Genes
Description
Regulation
''psdA'': induced by nisin, gallidermin (PsdR) PubMed
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psdApsdB

2025-01-17 14:46:12

ghost

78

528cfddc9a2a0d8255143057e419a826bbda2cca

A575053EE656C7505582CC0B07D1C34F3FE06BD1

Biological materials
Mutant
MGNA-B635 (yvcR::erm), available at the NBRP B. subtilis, Japan
BKE34700 (psdA::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTTCTGCTCCTCCTTTT,  downstream forward: _UP4_TTGAGTGTGTTGGGAGGCGA
BKK34700 (psdA::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTTCTGCTCCTCCTTTT,  downstream forward: _UP4_TTGAGTGTGTTGGGAGGCGA
References
Reviews
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Original Publications
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464DD1855E6B3195EE242637612A16C73FF32FC0

Page visits: 5724

Time of last update: 2025-01-18 08:47:45

Author of last update: Jstuelk