dacC
168
Class C penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
Locus
BSU_18350
Molecular weight
52.72 kDa
Isoelectric point
5.41
Function
carboxypeptidase
Product
penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
Essential
no
Synonyms
dacC, pbp
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2027 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,998,340 1,999,815
The protein
Catalyzed reaction/ biological activity
cleavage ofD-Ala-D-Ala interpeptide bridges in peptidoglycan PubMed
Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine (according to UniProt)
Protein family
peptidase S13 family (single member, according to UniProt)
Structure
Expression and Regulation
Operons
Biological materials
Mutant
MGNA-B075 (dacC::erm), available at the NBRP B. subtilis, Japan
GFP fusion
References
Reviews
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Original Publications
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Time of last update: 2025-02-23 09:01:02
Author of last update: Jstuelk