pdaB

pdaB
168

polysaccharide deacetylase

Locus
BSU_01570
Molecular weight
28.17 kDa
Isoelectric point
9.18
Protein length
254 aaSequenceBlast
Gene length
765 bpSequenceBlast
Function
spore cortex formation
Product
polysaccharide deacetylase
Essential
no
Synonyms
pdaB, ybaN
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0726 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
159,779 → 160,543
Phenotypes of a mutant
''pdaB ytrI and pdaB ytrH'' mutants are deficient in sporulation
inactivation of ''pdaB'' reduces sporulation efficiency to 5% that of wild type cells PubMed
The protein
Protein family
polysaccharide deacetylase family (according to UniProt)
Domains
NodB homology domain (aa 57-237) (according to UniProt)
Structure
4M1B (PDB) (from B. anthracis, 54% identity) PubMed
P50865 (AlphaFold)
Localization
forespore (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
pdaB
Description
PubMed
Regulation
expressed during sporulation in the mother cell PubMed
Regulatory mechanism
SpoIIID: repression, PubMed, in spoIIID regulon
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
Additional information
the mRNA is very stable (half-life > 15 min) PubMed
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pdaB

2025-03-10 07:01:34

ghost

72

358a01d8ef43d9e62523f53fc77567ec56eb9368

B1B82D686558D48B262D952EBAD12DA72EB925CB

Biological materials
Mutant
MGNA-B947 (ybaN::erm), available at the NBRP B. subtilis, Japan
BKE01570 (ΔpdaB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACTGATGATGCCTCCTTAT,  downstream forward: _UP4_GCCAAATCCGCAGAGGTAAA
BKK01570 (ΔpdaB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACTGATGATGCCTCCTTAT,  downstream forward: _UP4_GCCAAATCCGCAGAGGTAAA
References
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Time of last update: 2025-04-06 03:50:40

Author of last update: Melvin.boenninger