ywaD
168
double-zinc aminopeptidase
locus
BSU_38470
Molecular weight
49.29 kDa
pI
6.64
function
unknown
product
double-zinc aminopeptidase
essential
no
synonyms
ywaD, ipa-8r
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2234 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,948,555 3,949,922
The protein
Catalyzed reaction/ biological activity
Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys (according to UniProt)
Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids (according to UniProt)
Protein family
peptidase M28 family (single member, according to UniProt)
Structure
[PDB|6HC6]
[PDB|6HC7]
[AF|P25152]
[wiki|Localization]
extracellular (signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
Biological materials
Mutant
MGNA-B678 (ywaD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1677 NBRP B. subtilis, Japan]
BKE38470 ([gene|162B960244B0E1334F9E99E7E0F050D3312830E5|ywaD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38470 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAAAATAAACCTCCCC, downstream forward: _UP4_TAAAAAAAGACGGCACTTGG
BKK38470 ([gene|162B960244B0E1334F9E99E7E0F050D3312830E5|ywaD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38470 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAAAATAAACCTCCCC, downstream forward: _UP4_TAAAAAAAGACGGCACTTGG
References
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Time of last update: 2025-01-21 21:00:27
Author of last update: Mparker