smpB

smpB
168

tmRNA-binding protein

Locus
BSU_33600
Molecular weight
17.95 kDa
Isoelectric point
10.42
Protein length
Gene length
Function
trans-translation
Product
tmRNA-binding protein
Essential
no
Synonyms
smpB, yvaI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0691 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,451,248 → 3,451,718
Phenotypes of a mutant
impaired growth at high and low temperatures PubMed
inactivation of ''smpB'' reduces sporulation efficiency to 23% that of wild type cells; delayed entry into sporulation PubMed
a brfA smpB double mutant has a severe growth defect PubMed
a rcqH smpB double mutant has a severe growth defect PubMed
The protein
Protein family
smpB family (single member, according to UniProt)
Structure
1P6V (PDB) (from Aquifex aeolicus, 55% identity, complex with the tRNA domain of SsrA) PubMed
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Description
Regulation
''yvaK'': induced by stress (SigB) PubMed
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
Open in new tab

secGssrA

2025-01-10 01:13:17

ghost

91

5b644e318b4e03f8229d1f7804ae24c07fdeb5dd

238E5C487975E311E1EBD32D07A14F173B276AD8

Genes
Description
Regulation
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smpBssrA

2025-01-29 08:59:14

ghost

108

79314a3579b82df76918096ecacc3b7bd94ed6b9

3806406E5CBA52123D5A75B46E96105A42099755

Description
Regulation
''yvaK'': induced by stress (SigB) PubMed
Open in new tab

yvaKssrA

2024-12-14 05:59:45

ghost

87

d8154c99b5174d2c9614c36d072e1652057bf9f1

E221678AD029D36CCA9613ABC361FB40A01462F7

Biological materials
Mutant
MGNA-A494 (yvaI::erm), available at the NBRP B. subtilis, Japan
BKE33600 (ΔsmpB::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGCCAGAACCTCCTCTCT,  downstream forward: _UP4_TAAAGGCATAGTGCTTGATT
BKK33600 (ΔsmpB::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGCCAGAACCTCCTCTCT,  downstream forward: _UP4_TAAAGGCATAGTGCTTGATT
Labs working on this gene/protein
Chet Price, Davis, USA homepage
References
Reviews
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Original Publications
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D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A

Page visits: 2944

Time of last update: 2025-01-27 15:08:38

Author of last update: Jstuelk