truA
168
pseudouridylate synthase I, universally conserved protein
Locus
BSU_01480
Molecular weight
27.90 kDa
Isoelectric point
6.65
Function
tRNA modification
Product
pseudouridylate synthase I
Essential
no
E.C.
5.4.99.12
Synonyms
truA, ybaH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0101 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
152,937 153,680
The protein
Catalyzed reaction/ biological activity
tRNA uridine38-40 --> tRNA pseudouridine38-40 (according to UniProt)
Protein family
tRNA pseudouridine synthase TruA family (single member, according to UniProt)
Structure
1VS3 (PDB) (from Thermus thermophilus, 42% identity) PubMed
Additional information
Expression and Regulation
Operons
Description
Regulation
expression is reduced in motile cells as compared to non-motile cells PubMed
Regulatory mechanism
stringent response: negative regulation, PubMed, in stringent response
Biological materials
Mutant
References
Loading
Page visits: 3493
Time of last update: 2025-01-25 23:54:50
Author of last update: Melvin.boenninger