rex

rex
168

transcriptional repressor of anaerobically expressed genes involved in anaerobic respiration and fermentation

Locus
BSU_05970
Molecular weight
23.95 kDa
Isoelectric point
6.77
Protein length
Gene length
Function
regulation of fermentation and anaerobic respiration
Product
transcriptional repressor
Essential
no
Synonyms
rex, ydiH

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2344 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
647,091 → 647,738
Phenotypes of a mutant
inactivation of ''rex'' reduces sporulation efficiency to 9.2% that of wild type cells PubMed
inactivation of ''rex'' confers resistance to high concentrations of Zn(II) PubMed
The protein
Protein family
transcriptional regulatory rex family (single member, according to UniProt)
Structure
Effectors of protein activity
NADH (indication of low oxygen concentration) releases Rex from DNA PubMed, Rex has a very high affinity for NADH
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Description
Regulation
constitutitvely expressed PubMed
the mRNA is processed between rex and tatAY by RNase Y, this requires the RicA-RicF-RicT complex PubMed
Open in new tab

ydiGtatCY

2025-01-06 20:54:39

Jstuelk

62

c85bb146dcdc740e3e21e01dea58cd7fd7dc9315

77618D8DC4FC5B69859BD5D38C3215E1FA8D50DF

Biological materials
Mutant
MGNA-C201 (ydiH::erm), available at the NBRP B. subtilis, Japan
LUW292 (erm), GP834 (erm), both available in the Stülke lab
BKE05970 (Δrex::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CGGAATTTTTGATTGATCCT,  downstream forward: _UP4_TAGAGGGAAAGGAGGAGCCC
BKK05970 (Δrex::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CGGAATTTTTGATTGATCCT,  downstream forward: _UP4_TAGAGGGAAAGGAGGAGCCC
Labs working on this gene/protein
Claes von Wachenfeldt, Lund University, Sweden Homepage
References
Reviews
Loading
Original Publications
Loading

B5EF521437323EF43F08E5EFDB5C798616CA499A

Page visits: 4727

Time of last update: 2025-01-23 05:41:58

Author of last update: Melvin.boenninger