xylB

xylB
168

xylulokinase

Locus
BSU_17610
Molecular weight
55.25 kDa
Isoelectric point
6.46
Protein length
499 aaSequenceBlast
Gene length
1500 bpSequenceBlast
Function
utilization of xylan and xylose
Product
xylulokinase
Essential
no
E.C.
2.7.1.17
Synonyms
xylB, yncA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1070 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,893,396 → 1,894,895
The protein
Catalyzed reaction/ biological activity
ATP + D-xylulose --> ADP + D-xylulose 5-phosphate + H+ (according to UniProt)
Protein family
FGGY kinase family (according to UniProt)
Structure
2NLX (PDB) (from E. coli, 35% identity, 52% similarity) PubMed
P39211 (AlphaFold)
Expression and Regulation
Operons
Genes
xylA-xylB
Description
PubMed
Regulation
carbon catabolite repression (CcpA) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
XylR: repression, PubMed, in xylR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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xylA→xylB

2025-04-07 12:36:23

ghost

102

03ab48d2da7656afb5bebb25c49c9a7a060c0932

CFA5B475783918BA5946A0FB73EFAFE093A8416B

Biological materials
Mutant
GP1151 (del aphA3) available in Stülke lab
1A719 (no resistance), PubMed, available at BGSC
BKE17610 (ΔxylB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTTCACTCCTTGCCC,  downstream forward: _UP4_TAATGATGTTATTGTCTGGA
BKK17610 (ΔxylB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTTCACTCCTTGCCC,  downstream forward: _UP4_TAATGATGTTATTGTCTGGA
Labs working on this gene/protein
Wolfgang Hillen, Erlangen University, Germany Homepage
References
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F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13

Page visits: 4250

Time of last update: 2025-04-06 11:00:50

Author of last update: Melvin.boenninger