xylR

xylR
168

transcriptional repressor of the xylA-xylB and xynP-xynB operons

Locus
BSU_17590
Molecular weight
38.29 kDa
Isoelectric point
5.82
Protein length
350 aaSequenceBlast
Gene length
1053 bpSequenceBlast
Function
regulation of xylan and xylose utilization
Product
transcriptional repressor
Essential
no
Synonyms
xylR
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1940 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,890,512 → 1,891,564
The protein
Catalyzed reaction/ biological activity
transcription repression of the ''xylA-xylB and the xynP-xynB'' operons
Protein family
ROK (NagC/XylR) family (with GmuE and GlcK, according to UniProt)
Structure
5F7R (PDB) (Rok from Listeria monocytogenes, 28% identity) PubMed
P94490 (AlphaFold)
Effectors of protein activity
inducer: xylose
Paralogous protein(s)
GlcK
Expression and Regulation
Operons
Genes
xylR
Description
PubMed
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xylR

2025-04-07 17:22:48

Jstuelk

74

5ec0e565b3c1e69f75ab8bd8f2486da1c01bd5c9

1ECA2467CD869662C4EAE6B919BBED02427959DF

Biological materials
Mutant
GP270 (erm), GP1302 (aphA3), available in the Stülke lab
BKE17590 (ΔxylR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACTTCATCCACTCCATTTG,  downstream forward: _UP4_TAATTTTTTATGGAATGGAC
BKK17590 (ΔxylR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACTTCATCCACTCCATTTG,  downstream forward: _UP4_TAATTTTTTATGGAATGGAC
Labs working on this gene/protein
Wolfgang Hillen, Erlangen University, Germany
References
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AF4395D134485290F4AA307B48494FED39E52CD7

Page visits: 8341

Time of last update: 2025-04-08 17:48:05

Author of last update: Melvin.boenninger