dnaX

dnaX
168

DNA polymerase III (gamma and tau subunits) part of the clamp-loader complex and the replisome

Locus
BSU_00190
Molecular weight
62.53 kDa
Isoelectric point
5.49
Protein length
563 aaSequenceBlast
Gene length
1692 bpSequenceBlast
Function
DNA replication
Product
DNA polymerase  III (gamma and tau subunits)
Essential
yes
E.C.
2.7.7.7
Synonyms
dnaX, dnaH, dna-8132
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2812 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
26,814  28,505
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
deoxyribonucleoside 5'-triphosphate + DNA(n) --> diphosphate + DNA(n+1) (according to UniProt)
required for bacteriophage SPP1 replication PubMed
Protein family
DnaX/STICHEL family (single member, according to UniProt)
Structure
1JR3 (PDB) (from E. coli, 39% identity) PubMed
P09122 (AlphaFold)
Localization
forms foci PubMed
Nucleoid (Mid-cell) PubMed
Expression and Regulation
Operons
Genes
dnaX-yaaK-recR-yaaL-bofA
Description
PubMed
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dnaX→bofA

2025-04-04 19:45:06

Jstuelk

152

1a32cdecddaee24171f48459041fdcb062bafc36

7EC4B7D4D9D0E5E8848420FD5562059E4207233C

References
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Page visits: 9449

Time of last update: 2025-04-06 03:45:25

Author of last update: Jstuelk