rlmH

rlmH
168

pseudouridine methyltransferase, required for methylation of pseudouridine at position 1944 of 23S rRNA

Locus
BSU_40230
Molecular weight
17.93 kDa
Isoelectric point
9.31
Protein length
159 aaSequenceBlast
Gene length
480 bpSequenceBlast
Function
maturation of 23S rRNA
Product
pseudouridine methyltransferase
Essential
no
E.C.
null
Synonyms
yydA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1576 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,134,436  4,134,915
The protein
Catalyzed reaction/ biological activity
pseudouridine1944 in 23S rRNA + S-adenosyl-L-methionine --> H+ + N3-methylpseudouridine1944 in 23S rRNA + S-adenosyl-L-homocysteine PubMed
Protein family
RNA methyltransferase rlmH family (single member, according to UniProt)
Structure
1TO0 (PDB)
Q45601 (AlphaFold)
Expression and Regulation
Operons
Genes
rlmH
Description
null
Regulatory mechanism
DnaA: repression, PubMed, in dnaA regulon
Open in new tab

rlmH

2025-03-10 01:14:10

Bzhu

67

a2480d1bfa95546f41edefa30265965a9b6cef77

67DC02B23005B8954A0054A619C76112D4636D1F

Genes
yyzF-rlmH-yydB-yydC-yydD
Description
PubMed
Open in new tab

yyzF->yydD

2025-04-03 14:28:48

Bzhu

90

48bf75e020e9f5fd2d9ef59908887dc7ee7a7e9f

E52B301591E08560585C6B02A1CBBF57AAE5EF23

Biological materials
Mutant
MGNA-B814 (yydA::erm), available at the NBRP B. subtilis, Japan
References
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AC2A9DC3DA569231442582A95EDB2A98BA335184

Page visits: 4666

Time of last update: 2025-04-03 19:37:02

Author of last update: Jstuelk