lutP

lutP
168

lactate permease

Locus
BSU_34190
Molecular weight
59.59 kDa
Isoelectric point
9.48
Protein length
563 aaSequenceBlast
Gene length
1692 bpSequenceBlast
Function
lactate uptake
Product
lactate permease
Essential
no
Synonyms
lutP, yvfH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1620 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,510,780 → 3,512,471
Phenotypes of a mutant
poor growth with lactate as single carbon source PubMed
The protein
Catalyzed reaction/ biological activity
lactate uptake PubMed
Protein family
lactate permease family (with LctP, according to UniProt)
Structure
P71067 (AlphaFold)
Paralogous protein(s)
LctP
Localization
membrane PubMed
Expression and Regulation
Operons
Genes
lutP
Description
PubMed
Regulation
expressed at high cell density (ComA) PubMed
Regulatory mechanism
ComA: activation, (ComA) PubMed, in comA regulon
LutR: repression, in lutR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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lutP

2025-04-04 08:07:20

ghost

84

4d0a139f9c188bf8fb1d1ab5397a4e19d54a602b

A3F48CABDA805CB9E58EED1FC0BD3CFC9B204033

Biological materials
Mutant
MGNA-A489 (yvfH::erm), available at the NBRP B. subtilis, Japan
BKE34190 (ΔlutP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCCAAACCCCTCCTTGA,  downstream forward: _UP4_TAAAAAAATCCTCCCGTCTA
BKK34190 (ΔlutP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCCAAACCCCTCCTTGA,  downstream forward: _UP4_TAAAAAAATCCTCCCGTCTA
GP4219 (lutP::phleo), available in Jörg Stülke's lab
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
References
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E607B0D57398BCCF64CF3CE2110E632B0C3A109E

Page visits: 5611

Time of last update: 2025-04-09 03:17:54

Author of last update: Christoph.elfmann