Difference between revisions of "Metabolism of signalling nucleotides"
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* [[GdpP]] | * [[GdpP]] | ||
* [[PgpH]] | * [[PgpH]] | ||
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===Protein potentially involved in c-di-GMP metabolism and signalling=== | ===Protein potentially involved in c-di-GMP metabolism and signalling=== | ||
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==Important original publications== | ==Important original publications== | ||
| − | <pubmed>21566650 22981860 23192352 23671116 23893111 24141192 24163341 25433025 25605304 26951678</pubmed> | + | <pubmed>21566650 22981860 23192352 23671116 23893111 24141192 24163341 25433025 25605304 26951678 22821967 28965724 </pubmed> |
==Important reviews== | ==Important reviews== | ||
| − | <pubmed>21255104 16045609 17208514 19756011 19287449 18714086 23023210 23812326 25636134 25869574,26773214 27354347</pubmed> | + | <pubmed>21255104 16045609 17208514 19756011 19287449 18714086 23023210 23812326 25636134 25869574,26773214 27354347 |
| + | 27149325</pubmed> | ||
=Back to [[categories]]= | =Back to [[categories]]= | ||
Latest revision as of 10:10, 3 October 2017
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Contents
- 1 Genes in this functional category
- 2 Important original publications
- 3 Important reviews
- 4 Back to categories
Genes in this functional category
ppGpp synthesis and degradation
c-di-AMP synthesis
Control of c-di-AMP synthesis
Note that c-di-AMP is essential for the growth of B. subtilis, but accumulation of the nucleotide is detrimental as well PubMed
c-di-AMP degradation
Protein potentially involved in c-di-GMP metabolism and signalling
Proteins containing a GGDEF domain (potential diguanylate cyclases)
- DgcK, has cyclase activity
- DgcW, has cyclase activity, contains both a GGDEF and an EAL domain
- DgcP, has cyclase activity
- YdaK, no activity, degenerate GGDEF domain
- GdpP, no diguanylate cyclase activity, is c-di-AMP specific phosphodiesterase (see above), degenerate GGDEF domain
Proteins containing an EAL domain (potential c-di-GMP phosphodiesterases)
- PdeH, has phosphodiesterase activity
- YkuI, no phosphodiesterase activity
- DgcW, phosphodiesterase activity not demonstrated, contains both a GGDEF and an EAL domain
Targets of signalling nucleotides
- c-di-GMP targets
- DgrA (contains a PilZ domain)
Important original publications
Important reviews
