yrbD

yrbD
168

sodium/proton-dependent alanine transporter

Locus
BSU_27810
Molecular weight
51.43 kDa
Isoelectric point
9.38
Protein length
484 aaSequenceBlast
Gene length
1455 bpSequenceBlast
Function
uptake of alanine
Product
sodium/proton-dependent alanine transporter
Essential
no
Synonyms
yrbD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1115 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,841,611  2,843,065
The protein
Protein family
Alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family (according to UniProt)
Structure
6CSE (PDB) (sodium/alanine symporter from Methanococcus maripaludis S2, 37% identity) PubMed
O32060 (AlphaFold)
Paralogous protein(s)
YflA, AlsT, GlnT
Expression and Regulation
Operons
Genes
yrbD
Description
PubMed
Regulatory mechanism
TnrA: activation, in tnrA regulon
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yrbD

2025-03-15 03:20:00

Bzhu

57

51fe4667297210d6e6f5466cae5aa4de2c171fb2

84A690FF65BD199AD0141D164E5C0F27CACDAFDF

Biological materials
Mutant
GP3556 (ΔyrbD::phleo), available in Jörg Stülke's lab
MGNA-A821 (yrbD::erm), available at the NBRP B. subtilis, Japan
BKE27810 (yrbD::erm  trpC2) available at BGSC and in Jörg Stülke's lab,  PubMed, upstream reverse: _UP1_CATCAAGCTTCCCCCTCACT,  downstream forward: _UP4_TGAACATACTAAAACCGGCC
BKK27810 (yrbD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCAAGCTTCCCCCTCACT,  downstream forward: _UP4_TGAACATACTAAAACCGGCC
Expression vectors
pGP4013: expression of yrbD (gapA RBS) by pBQ200 in B. subtilis, available in Jörg Stülke's lab
References
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Page visits: 3107

Time of last update: 2025-04-09 09:13:43

Author of last update: Robert.warneke