gntK

gntK
168

gluconokinase

Locus
BSU_40060
Molecular weight
57.00 kDa
Isoelectric point
5.52
Protein length
Gene length
Function
gluconate utilization
Product
gluconokinase
Essential
no
E.C.
2.7.1.12
Synonyms
gntK

Genomic Context

List of homologs in different organisms, belongs to COG1070 (Galperin et al., 2021)

This gene is a member of the following regulons

SigA regulon, CcpA regulon, AbrB regulon, GntR regulon

Gene
Coordinates
4,114,141  4,115,682
The protein
Catalyzed reaction/ biological activity
ATP + D-gluconate --> 6-phospho-D-gluconate + ADP + H+ (according to UniProt)
Protein family
FGGY kinase family (according to UniProt)
Structure
3GBT (PDB) (from Lactobacillus acidophilus, 39% identity)
Expression and Regulation
Operons
Description
Regulation
induced by gluconate (GntR) PubMed
Regulatory mechanism
GntR: repression, PubMed, in gntR regulon
CcpA: repression, PubMed, in ccpA regulon
AbrB: activation, PubMed, in abrB regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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gntRgntZ

2025-01-25 10:03:39

ghost

74

a4a9f34acee86d883fafe2368089737d1c13df10

02F8B40AEEBB8D4A2614150F30482A3F72134EF4

Biological materials
Mutant
BKE40060 (gntK::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_GCCGATATCGATTCCTAACA,  downstream forward: _UP4_TAGTACATGACATGAAGGGG
BKK40060 (gntK::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_GCCGATATCGATTCCTAACA,  downstream forward: _UP4_TAGTACATGACATGAAGGGG
References
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72404FA6ECD62AEA3EFDB934DFB8DA581875605C

Page visits: 3161

Time of last update: 2025-01-27 08:37:49

Author of last update: Melvin.boenninger