Difference between revisions of "PbpI"
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− | * '''Description:''' penicillin-binding protein | + | * '''Description:''' sporulation-specific [[penicillin-binding protein]] 4b <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || penicillin-binding protein | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[penicillin-binding protein]] 4b |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown | |style="background:#ABCDEF;" align="center"|'''Function''' || unknown | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27310 pbpI] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 65 kDa, 9.012 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 65 kDa, 9.012 | ||
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1752 bp, 584 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1752 bp, 584 aa | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrrS]]'', ''[[greA]]'' |
|- | |- | ||
− | |style="background:#FAF8CC;" align="center"|'''[http:// | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27310 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27310 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27310 DNA_with_flanks] |
− | |||
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yrrR_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yrrR_context.gif]] | ||
+ | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pbpI_2789686_2791440_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:pbpI_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27310]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | |||
<br/><br/> | <br/><br/> | ||
+ | |||
+ | = [[Categories]] containing this gene/protein = | ||
+ | {{SubtiWiki category|[[cell wall synthesis]]}}, | ||
+ | {{SubtiWiki category|[[sporulation proteins]]}} | ||
+ | |||
+ | = This gene is a member of the following [[regulons]] = | ||
+ | {{SubtiWiki regulon|[[SigE regulon]]}}, | ||
+ | {{SubtiWiki regulon|[[SigF regulon]]}} | ||
=The gene= | =The gene= | ||
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=== Basic information === | === Basic information === | ||
− | * ''' | + | * '''Locus tag:''' BSU27310 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27310&redirect=T BSU27310] | ||
− | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ | + | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yrrRS.html] |
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13797] | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13797] | ||
=== Additional information=== | === Additional information=== | ||
+ | |||
+ | |||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
− | * '''Protein family:''' | + | * '''Protein family:''' [[transpeptidase family]] (according to UniProt) |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
+ | ** may be part of the [[cell wall biosynthetic complex]] {{PubMed|17981078}} | ||
− | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27310&redirect=T BSU27310] | ||
* '''Structure:''' | * '''Structure:''' | ||
− | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/O32032 O32032] |
− | * '''KEGG entry:''' | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27310] |
* '''E.C. number:''' | * '''E.C. number:''' | ||
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=Expression and regulation= | =Expression and regulation= | ||
+ | * '''Operon:''' ''[[pbpI]]-[[yrrS]]'' (according to [http://dbtbs.hgc.jp/COG/prom/yrrRS.html DBTBS]) | ||
− | * ''' | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pbpI_2789686_2791440_-1 pbpI] {{PubMed|22383849}} |
− | * '''Sigma factor:''' [[SigE]] [ | + | * '''Sigma factor:''' [[SigE]] {{PubMed|14679248,15758244}}, [[SigF]] {{PubMed|15699190,16497325}} |
− | * '''Regulation:''' expressed during sporulation in | + | * '''Regulation:''' |
+ | ** expressed early during sporulation in both cell compartments ([[SigE]] {{PubMed|14679248,15758244}}, [[SigF]] {{PubMed|15699190,16497325}}) | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Line 117: | Line 142: | ||
=References= | =References= | ||
+ | <pubmed>14679248 15699190,16497325 ,15758244 </pubmed> | ||
− | + | [[Category:Protein-coding genes]] |
Latest revision as of 09:12, 26 June 2019
- Description: sporulation-specific penicillin-binding protein 4b
Gene name | pbpI |
Synonyms | yrrR |
Essential | no |
Product | penicillin-binding protein 4b |
Function | unknown |
Gene expression levels in SubtiExpress: pbpI | |
MW, pI | 65 kDa, 9.012 |
Gene length, protein length | 1752 bp, 584 aa |
Immediate neighbours | yrrS, greA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell wall synthesis, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27310
Phenotypes of a mutant
Database entries
- BsubCyc: BSU27310
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: transpeptidase family (according to UniProt)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- may be part of the cell wall biosynthetic complex PubMed
Database entries
- BsubCyc: BSU27310
- Structure:
- UniProt: O32032
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References