pgpB

pgpB
168

phosphatidylglycerol phosphate (PGP) phosphatase , has minor undecaprenyl pyrophosphate phosphatase activity

Locus
BSU_19650
Molecular weight
22.64 kDa
Isoelectric point
10.14
Protein length
Gene length
Function
phospholipid biosynthesis
Product
phosphatidylglycerol phosphate (PGP) phosphatase
Essential
no
Synonyms
yodM

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0671 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,136,913  2,137,524
The protein
Catalyzed reaction/ biological activity
1,2-diacyl-sn-glycero-3-phospho-(1ʼ-sn-glycero-3ʼ-phosphate) + H2O --> 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate (according to UniProt)
Protein family
PA-phosphatase related phosphoesterase family (single member, according to UniProt)
Structure
cell membrane (integral) PubMed
Expression and Regulation
Additional information
the mRNA is cleaved by RNase III PubMed
Biological materials
Mutant
GP3652 ΔpgpB::cat, available in Jörg Stülke's lab
GP3680 ΔpgpB::aphA3, available in Jörg Stülke's lab
MGNA-B441 (pgpB::erm), available at the NBRP B. subtilis, Japan
BKE19650 (pgpB::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAATTTTAACCACCTCAATT,  downstream forward: _UP4_TAGAGAGAGGAAAACACAGC
BKK19650 (pgpB::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAATTTTAACCACCTCAATT,  downstream forward: _UP4_TAGAGAGAGGAAAACACAGC
FLAG-tag construct
GP3675 (spc, based on pGP1331), available in Jörg Stülke's lab
References
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Time of last update: 2025-01-20 20:18:57

Author of last update: Rica