Difference between revisions of "NadD"
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25640 nadD] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25640 nadD] | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=NadD NadD]''' | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.123 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.123 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqeK]]'', ''[[yqeI]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqeK]]'', ''[[yqeI]]'' | ||
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| − | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25640 | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25640 DNA_with_flanks] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:yqeJ_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yqeJ_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nadD_2643765_2644334_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:nadD_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nadD_2643765_2644334_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:nadD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25640]] |
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|} | |} | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25640&redirect=T BSU25640] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25640&redirect=T BSU25640] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1KAQ 1KAQ] | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1KAQ 1KAQ] | ||
Latest revision as of 11:48, 8 April 2014
- Description: nicotinamide-nucleotide adenylyltransferase
| Gene name | nadD |
| Synonyms | yqeJ |
| Essential | yes PubMed |
| Product | nicotinamide-nucleotide adenylyltransferase |
| Function | NAD biosynthesis |
| Gene expression levels in SubtiExpress: nadD | |
| Metabolic function and regulation of this protein in SubtiPathways: NadD | |
| MW, pI | 22 kDa, 5.123 |
| Gene length, protein length | 567 bp, 189 aa |
| Immediate neighbours | yqeK, yqeI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25640
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU25640
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+ (according to Swiss-Prot)
- Protein family: nadD family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU25640
- Structure: 1KAQ
- UniProt: P54455
- KEGG entry: [2]
- E.C. number: 2.7.7.18
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Andrea M Olland, Kathryn W Underwood, Robert M Czerwinski, Mei-Chu Lo, Ann Aulabaugh, Joel Bard, Mark L Stahl, William S Somers, Francis X Sullivan, Rajiv Chopra
Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase.
J Biol Chem: 2002, 277(5);3698-707
[PubMed:11704676]
[WorldCat.org]
[DOI]
(P p)
