Difference between revisions of "YdaO riboswitch"

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(This riboswitch controls the expression of the ydaO gene and the ktrA-ktrB operon. Gene expression is decreased upon binding of ATP to the riboswitch. In consequence, the target genes are induced if the energy charge of the cell is low.)
 
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==This [[riboswitch]] controls the expression of the ''[[ydaO]]'' gene and the ''[[ktrA]]-[[ktrB]]'' operon. Gene expression is decreased upon binding of ATP to the [[riboswitch]]. In consequence, the target genes are induced if the energy charge of the cell is low. ==
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==This [[riboswitch]] controls the expression of the ''[[ydaO]]'' gene and the ''[[ktrA]]-[[ktrB]]'' operon. Gene expression is decreased upon binding of c-di-AMP to the [[riboswitch]]. ==
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==Structure of the riboswitch: [http://www.rcsb.org/pdb/explore/explore.do?structureId=4W90 4W90]==
  
 
==References==
 
==References==
<pubmed>15096624,20511502 23086297 </pubmed>
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<pubmed>15096624,20511502 23086297 24141192 25086509 25086507 25271255 25869574 </pubmed>
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=See also:=
 
=See also:=
 
* [[RNA switch]]
 
* [[RNA switch]]
  
 
=Back to [[regulons]]=
 
=Back to [[regulons]]=

Latest revision as of 14:03, 14 August 2015

This riboswitch controls the expression of the ydaO gene and the ktrA-ktrB operon. Gene expression is decreased upon binding of c-di-AMP to the riboswitch.

Structure of the riboswitch: 4W90

References

Fabian M Commichau, Achim Dickmanns, Jan Gundlach, Ralf Ficner, Jörg Stülke
A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP.
Mol Microbiol: 2015, 97(2);189-204
[PubMed:25869574] [WorldCat.org] [DOI] (I p)

Christopher P Jones, Adrian R Ferré-D'Amaré
Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
EMBO J: 2014, 33(22);2692-703
[PubMed:25271255] [WorldCat.org] [DOI] (I p)

Aiming Ren, Dinshaw J Patel
c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.
Nat Chem Biol: 2014, 10(9);780-6
[PubMed:25086509] [WorldCat.org] [DOI] (I p)

Ang Gao, Alexander Serganov
Structural insights into recognition of c-di-AMP by the ydaO riboswitch.
Nat Chem Biol: 2014, 10(9);787-92
[PubMed:25086507] [WorldCat.org] [DOI] (I p)

James W Nelson, Narasimhan Sudarsan, Kazuhiro Furukawa, Zasha Weinberg, Joy X Wang, Ronald R Breaker
Riboswitches in eubacteria sense the second messenger c-di-AMP.
Nat Chem Biol: 2013, 9(12);834-9
[PubMed:24141192] [WorldCat.org] [DOI] (I p)

Peter Y Watson, Martha J Fedor
The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis.
Nat Chem Biol: 2012, 8(12);963-5
[PubMed:23086297] [WorldCat.org] [DOI] (I p)

Kirsten F Block, Ming C Hammond, Ronald R Breaker
Evidence for widespread gene control function by the ydaO riboswitch candidate.
J Bacteriol: 2010, 192(15);3983-9
[PubMed:20511502] [WorldCat.org] [DOI] (I p)

Jeffrey E Barrick, Keith A Corbino, Wade C Winkler, Ali Nahvi, Maumita Mandal, Jennifer Collins, Mark Lee, Adam Roth, Narasimhan Sudarsan, Inbal Jona, J Kenneth Wickiser, Ronald R Breaker
New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control.
Proc Natl Acad Sci U S A: 2004, 101(17);6421-6
[PubMed:15096624] [WorldCat.org] [DOI] (P p)


See also:

Back to regulons