ntdR

ntdR
168

transcription activator of the ntdA-ntdB-ntdC-glcP operon

Locus
BSU_10560
Molecular weight
37.53 kDa
Isoelectric point
6.64
Protein length
Gene length
Function
regulation of the ntdA-ntdB-ntdC-glcP operon
Product
transcriptional regulator (LacI family)
Essential
no
Synonyms
ntdR, yhjM

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,129,715  1,130,704
The protein
Catalyzed reaction/ biological activity
transcription activation of the ntdA-ntdB-ntdC-glcP operon PubMed
Protein family
HTH lacI-type domain (aa 2-56) (according to UniProt)
Structure
2HSG (PDB) (ccpA from B. megaterium, 31% identity) PubMed
Effectors of protein activity
3,3'-neotrehalosadiamine and kanosamine act as inducers PubMed
Expression and Regulation
Operons
Genes
Description
Regulatory mechanism
AbrB: repression, PubMed, in abrB regulon
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ntdR

2025-01-14 16:56:09

ghost

56

ddb3998a89db3f3508cf43feff564cc59bafa3a2

5146A3137E81E1583CFC63A1961870F3E72CB1CD

Biological materials
Mutant
MGNA-A726 (yhjM::erm), available at the NBRP B. subtilis, Japan
BKE10560 (ntdR::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATATTTTCCCTTCCTTAAA,  downstream forward: _UP4_TAACGATAGATTTCCCTTTA
BKK10560 (ntdR::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATATTTTCCCTTCCTTAAA,  downstream forward: _UP4_TAACGATAGATTTCCCTTTA
References
Reviews
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Original Publications
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9118A36CD30E7C99697B3659BB04E03BB7EE71D7

Page visits: 3143

Time of last update: 2025-01-18 12:50:14

Author of last update: Jstuelk