catD

catD
168

essential for viability in the presence of catechol

Locus
BSU_08230
Molecular weight
14.28 kDa
Isoelectric point
10.11
Protein length
134 aaSequenceBlast
Gene length
405 bpSequenceBlast
Function
detoxification of catechol
Product
unknown
Essential
no
Synonyms
catD, yfiD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2259 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
897,588 → 897,992
Phenotypes of a mutant
not viable in the presence of catechol PubMed
The protein
Protein family
DoxX family (with MhqP, according to UniProt)
Structure
P54720 (AlphaFold)
Localization
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
catD-catE
Description
PubMed
Regulation
strong induction by diamide and quinones (such as catechol) (YodB, CatR) PubMed
induced by iron starvation (Fur) PubMed
Regulatory mechanism
YodB: repression, PubMed, in yodB regulon
CatR: repression, PubMed, in catR regulon
Fur: repression, PubMed, in fur regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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catD→catE

2025-02-20 08:49:56

Jstuelk

59

917958761b4b1f416996a2a063990c7a6fd008bc

2DEC0ECC579FFD7C687FEF51E93AD14225EB14B4

Biological materials
Mutant
MGNA-C294 (yfiD::erm), available at the NBRP B. subtilis, Japan
BKE08230 (ΔcatD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTATCCTCCTTGATAA,  downstream forward: _UP4_GCATAAGAAAAGAGGCATGC
BKK08230 (ΔcatD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTATCCTCCTTGATAA,  downstream forward: _UP4_GCATAAGAAAAGAGGCATGC
References
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Time of last update: 2025-04-09 13:35:14

Author of last update: Melvin.boenninger