flgB

flgB
168

flagellar basal-body rod protein, required for the assembly of the flagellar hook and filament

Locus
BSU_16180
Molecular weight
14.30 kDa
Isoelectric point
5.16
Protein length
129 aaSequenceBlast
Gene length
390 bpSequenceBlast
Function
movement and chemotaxis
Product
flagellar basal-body rod protein
Essential
no
Synonyms
flgB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1815 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,691,278  1,691,667
Phenotypes of a mutant
defective in Swarming and flagellar assembly PubMed
The protein
Catalyzed reaction/ biological activity
part of the flagellar rod-hook (in FliE-FlgB-FlgC-FlhO-FlhP-FlgE out, connection to Hag) PubMed
Protein family
Flagella basal body rod proteins family (according to UniProt)
Structure
P24500 (AlphaFold)
Localization
bacterial flagellum basal body (according to Swiss-Prot),  extracellular (no signal peptide) PubMed
Expression and Regulation
Operons
Genes
flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-swrD-fliL-fliM-fliY-cheY-fliO-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB
Description
PubMed
Regulation
expression during spore germination is strongly reduced under conditions of osmotic stress PubMed
Regulatory mechanism
Spo0A: repression, in spo0A regulon
SwrA: activation, in swrA regulon
CodY: repression, in codY regulon
DegU: repression, in degU regulon
SinR: transcription elongation, binding of the SinR-SlrR heteromer to sites within fliE and fliI results in inhibition of transcription elongation PubMed, in sinR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigD: sigma factor, PubMed, in sigD regulon
Open in new tab

flgB→swrB

2025-04-03 01:56:48

Jstuelk

173

024d59ae468aa14568753f57122b789c39ed6c06

4D920B925DA071AE7390E022B9AB625E40B7B2AC

Biological materials
Mutant
a flgB::erm mutant is available in Linc Sonenshein's lab
1A922 ( flgB::erm), PubMed, available at BGSC
BKE16180 (flgB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAATCCACTTACCTCCATT,  downstream forward: _UP4_ACCGTATTAACAGGAGGAAA
BKK16180 (flgB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAATCCACTTACCTCCATT,  downstream forward: _UP4_ACCGTATTAACAGGAGGAAA
References
Loading

1C6C8DB02E10EAC0588389D9F0D3AF3E19172C5C

Page visits: 5779

Time of last update: 2025-04-09 02:30:47

Author of last update: Jstuelk