Difference between revisions of "Glutamate metabolism"

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(Proteins involved in glutamate metabolism)
 
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== Reviews ==
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= Proteins involved in glutamate metabolism =
<pubmed> 18086213 16458044 </pubmed>
 
  
==Regulation of glutamate synthase expression==
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=== Transport systems ===
<pubmed> 14523131 17183217 17608797 20630473 </pubmed>
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* Ammonium uptake: [[NrgA|AmtB]]
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* Glutamine uptake: [[GlnT]], [[GlnQ]]-([[GlnM]]-[[GlnP]])-[[GlnH]]
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* Glutamate uptake: [[YbeC]], [[GltT]]
  
==Regulatory protein-protein interactions in nitrogen regulation==
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=== Metabolic enzymes===
<pubmed> 17001076 17608797 </pubmed>
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* Glutamine synthetase: [[GlnA]]
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* Glutamate synthase: [[GltA]], [[GltB]]
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* Glutamate dehydrogenases: [[GudB]], [[RocG]]
  
== Glutamate homeostasis by  the acquisition of mutations ==
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=== Regulators ===
<pubmed> 18326565 21219666 22178973 </pubmed>
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* Key transcriptional regulators of nitrogen metabolism: [[GlnR]], [[GltC]], [[TnrA]]
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* Additional transcriptional regulators: [[AhrC]], [[RocR]], [[CcpA]], [[Fur]]
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* Control of ammonium uptake: [[NrgB|GlnK]]
  
== Additional stuff ==
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= Relevant ''Subti''Wiki pages =  
<pubmed> 14600241 20933603 </pubmed>
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* [[Biosynthesis/ acquisition of amino acids]]
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* [[Utilization of amino acids]]
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* [[TnrA regulon]]
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* [[GlnR regulon]]
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* [[GltC regulon]]
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* [[Trigger enzymes]]
  
== Methods ==
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= Glutamate metabolism in [[SubtiPathways]]: [http://subtiwiki.uni-goettingen.de/pathways/glutamate.html Ammonium/ glutamate] =
<pubmed> 17994626 </pubmed>
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= Additional websites =
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* [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34383&submit.x=22&submit.y=9 transcriptome analysis of a ''[[rocG]] [[gudB]]'' mutant vs. wild type]
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= Labs studying glutamate metabolism=
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* [[Fabian Commichau]], Göttingen, Germany
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* [[Susan Fisher]], Boston
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* [[Linc Sonenshein]], Boston
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* [[Jörg Stülke]], Göttingen
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= Important publications =
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==Reviews==
 +
<pubmed>18086213,17982469,16458044,10231480 22625175</pubmed>
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== Important original publications ==
 +
<pubmed>23811508 </pubmed>

Latest revision as of 10:44, 6 May 2021

Proteins involved in glutamate metabolism

Transport systems

Metabolic enzymes

Regulators

  • Key transcriptional regulators of nitrogen metabolism: GlnR, GltC, TnrA
  • Additional transcriptional regulators: AhrC, RocR, CcpA, Fur
  • Control of ammonium uptake: GlnK

Relevant SubtiWiki pages

Glutamate metabolism in SubtiPathways: Ammonium/ glutamate

Additional websites

Labs studying glutamate metabolism

Important publications

Reviews

Important original publications