gerD

gerD
168

scaffold of the germinosome, required for clustering of germinant receptors in the spore inner membrane

Locus
BSU_01550
Molecular weight
20.97 kDa
Isoelectric point
4.86
Protein length
Gene length
Function
germination
Product
lipoprotein
Essential
no
Synonyms
gerD

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5904 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
158,515  159,072
Phenotypes of a mutant
defective in germination in response to nutrients PubMed
The protein
Catalyzed reaction/ biological activity
required for clustering of germinant receptors in the spore inner membrane PubMed
has an N-terminal signal sequence and a signal for fixation to lipid PubMed
Structure
outer surface of the inner spore membrane PubMed
inner spore membrane, spore coat, cortex, germ cell wall, some GerD is also present in the soluble fraction PubMed
Additional information
3,500 molecules are present per spore PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
expression level depends on sporulation conditions (medim composition, temperature) PubMed
Sigma factors
SigF: sigma factor, PubMed, in sigF regulon
SigG: sigma factor, PubMed, in sigG regulon
Additional information
3,500 molecules are present per spore PubMed
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gerD

2025-02-25 19:57:26

ghost

93

4d937204f4c653e258eb65412311ee6bda2e3adc

F4E5BFF9FE2738D9DBEF91F942900C20586B0554

Biological materials
Mutant
1A677 ( gerD::erm), PubMed, available at BGSC
1G17 ( gerD::spec), PubMed, available at BGSC
BKE01550 (gerD::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGCTTAAGCTCCTTTCAC,  downstream forward: _UP4_TAAAGGGAAAGCCGGGATCT
BKK01550 (gerD::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGCTTAAGCTCCTTTCAC,  downstream forward: _UP4_TAAAGGGAAAGCCGGGATCT
Antibody
available in Anne Moir lab
Labs working on this gene/protein
Anne Moir, University of Sheffield, UK
References
Reviews
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Original Publications
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3E5B9AC0C6F974800DE1ABF25769D24947772DCB

Page visits: 5455

Time of last update: 2025-02-27 03:18:12

Author of last update: Jstuelk