appF

appF
168

oligopeptide ABC transporter (ATP-binding protein)

Locus
BSU_11370
Molecular weight
36.96 kDa
Isoelectric point
9.65
Protein length
Gene length
Function
uptake of oligopeptides
Product
oligopeptide ABC transporter (ATP-binding protein)
Essential
no
Synonyms
appF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0444 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,212,460 → 1,213,449
The protein
Protein family
ABC transporter superfamily (according to UniProt)
ABC transporter domain (aa 10-261) (according to UniProt)
Structure
4FWI (PDB) (dipeptide transporter from Thermoanaerobacter tengcongensis, 37% identity) PubMed
Paralogous protein(s)
attached to the cell membrane (via AppB-AppC) PubMed
Expression and Regulation
Operons
Description
Regulation
repressed by CodY PubMed
Regulatory mechanism
TnrA: activation, PubMed, in tnrA regulon
CodY: repression, PubMed PubMed, in codY regulon
ScoC: repression, PubMed, in scoC regulon
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appDappC

2025-01-21 18:40:32

Jstuelk

113

b46f08a2cd8f8540d1ae7be3ab793fb86c3b4d9c

D515582AF1C173F5A0D9E2C830FC884903502563

Biological materials
Mutant
GP2100 (D(''appD-appF-appA/2-appB-appC)::spc''), available in Jörg Stülke's lab
BKE11370 (ΔappF::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_TGTCATGATTGTTCGGCACC,  downstream forward: _UP4_TAATGTTGCCCGCACAGCTT
BKK11370 (ΔappF::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_TGTCATGATTGTTCGGCACC,  downstream forward: _UP4_TAATGTTGCCCGCACAGCTT
References
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Time of last update: 2025-01-22 08:24:48

Author of last update: Jstuelk