shfP

shfP
168

sporulation-specific phosphodiesterase

Locus
BSU_35040
Molecular weight
147.88 kDa
Isoelectric point
6.23
Protein length
Gene length
Function
control of sporulation entry in neighbor cells
Product
sporulation-specific phosphodiesterase
Essential
no
E.C.
null
Synonyms
yvnB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1409 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,598,040 → 3,601,909
Phenotypes of a mutant
inactivation of shfP suppresses the sporulation defect of a shfA mutant PubMed
The protein
Catalyzed reaction/ biological activity
generates extracellular glycerol, which delays entry of neighbor cells into sporulation PubMed
LTD domain (aa 141-277) (according to UniProt)
Structure
in the intermembrane macromolecular matrix surrounding the forespore PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
expressed late during sporulation in the forespore (SigG) PubMed bioRxiv
Sigma factors
SigG: sigma factor, bioRxiv, in sigG regulon
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shfP

2025-01-15 02:45:44

Jstuelk

62

65A3C58FBF2A607CE98015102B9D76ADA22EAB33

09A14BF953C8403F0734CBE0A63B9B1F053532B0

Biological materials
Mutant
MGNA-A338 (yvnB::erm), available at the NBRP B. subtilis, Japan
BKE35040 (ΔshfP::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCAAAGCACCTCCCTTTT,  downstream forward: _UP4_CCTTAAAAAGGGTTGGAGGC
BKK35040 (ΔshfP::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCAAAGCACCTCCCTTTT,  downstream forward: _UP4_CCTTAAAAAGGGTTGGAGGC
References
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Time of last update: 2025-01-27 02:12:41

Author of last update: Jstuelk