spoVID

spoVID
168

developmental checkpoint, co-ordinates spore cortex and coat assembly, spore coat morphogenetic protein, non-competitive hub during spore encasement, promotes encasement of the spore

Locus
BSU_28110
Molecular weight
64.80 kDa
Isoelectric point
4
Protein length
575 aaSequenceBlast
Gene length
1728 bpSequenceBlast
Function
spore coat assembly
Product
spore coat morphogenetic protein
Essential
no
Synonyms
spoVID
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5846 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,871,022  2,872,749
Phenotypes of a mutant
accumulation of SafA and CotE and their dependent proteins at the mother cell proximal spore pole PubMed
The protein
Catalyzed reaction/ biological activity
measures the successful polymerization of the coat basement layer PubMed
ensures orchestrated assembly of the spore envelope PubMed
Domains
contains a N-acetylglucosamine-polymer-binding LysM domain (aa 523-567) PubMed
LysM domain (aa 523-567) (according to UniProt)
Structure
P37963 (AlphaFold)
Localization
spore coat (basement), localization depends on SpoIVA PubMed
Expression and Regulation
Operons
Genes
spoVID-ysxE
Description
PubMed
Regulation
expressed early during sporulation in the mother cell (SigE) PubMed
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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spoVID→ysxE

2025-04-04 00:23:02

ghost

79

75576c35a548b943ad54cc70b3b06cc1aa256792

94B9AA3648B3DC3632D745D2108B15329C1C3EEC

Biological materials
Mutant
1A639 ( spoVID::erm), PubMed, available at BGSC
1S127 ( spoVID::erm), PubMed, available at BGSC
BKE28110 (spoVID::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGTTCATATCCTCCTTTC,  downstream forward: _UP4_TAAACCGTAAGTGATCGGAA
BKK28110 (spoVID::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGTTCATATCCTCCTTTC,  downstream forward: _UP4_TAAACCGTAAGTGATCGGAA
Labs working on this gene/protein
Adriano Henriques, Lisbon, Portugal homepage
Charles Moran, Emory University, NC, USA homepage
References
Reviews
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Original Publications
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6698BB092E03BEF48AFD0CBF565410109CD1ABB5

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Time of last update: 2025-04-10 08:11:12

Author of last update: Jstuelk