ahpT

ahpT
168

thiol disulfide oxidoreductase, reduces AhpA

Locus
BSU_14230
Molecular weight
17.66 kDa
Isoelectric point
6.33
Protein length
148 aaSequenceBlast
Gene length
447 bpSequenceBlast
Function
protection of proteins against oxidative damage
Product
thiol disulfide oxidoreductase
Essential
no
Synonyms
ahpT, ykuV
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0526 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,492,875  1,493,321
The protein
Domains
Thioredoxin domain (aa 2-145) (according to UniProt)
Structure
2B5X (PDB) (reduced form),  2B5Y (PDB) (oxidized form)
O31699 (AlphaFold)
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
ahpA-ahpT
Description
PubMed
Regulatory mechanism
AbrB: repression, PubMed, in abrB regulon
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ahpA→ahpT

2025-04-06 04:00:02

ghost

98

db3a077f5db973f301f5c2b07584b017a7d043c3

86001A08BE15B429348F69EB0340A4C6602B0430

Biological materials
Mutant
GP1729 ahpAT::kan trpC2 available in Jörg Stülke's lab
MGNA-B344 (ykuV::erm), available at the NBRP B. subtilis, Japan
BKE14230 (ahpT::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCTTTTTCCCTCCTAT,  downstream forward: _UP4_TAGGTATCTGACTAAATAGT
BKK14230 (ahpT::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCTTTTTCCCTCCTAT,  downstream forward: _UP4_TAGGTATCTGACTAAATAGT
References
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398E6FAC317D9BD81FB80A7CC9DF1CC757F2FA98

Page visits: 2897

Time of last update: 2025-04-08 18:57:00

Author of last update: Melvin.boenninger