cotS

cotS
168

outer spore coat protein

Locus
BSU_30900
Molecular weight
40.93 kDa
Isoelectric point
6.64
Protein length
351 aaSequenceBlast
Gene length
1056 bpSequenceBlast
Function
resistance of the spore
Product
spore coat protein
Essential
no
Synonyms
cotS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5881 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,159,691 → 3,160,746
The protein
Protein family
cotS family (with CotI and YutH, according to UniProt)
Structure
2Q83 (PDB) (CotI, 26% identity) PubMed
P46914 (AlphaFold)
Localization
outer spore coat, localization depends on CotE  PubMed
Expression and Regulation
Operons
Genes
cotSA-cotS-ytxO
Description
PubMed
Regulation
expressed late during sporulation in the mother cell (SigK) PubMed
Regulatory mechanism
GerE: activation, PubMed, in gerE regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
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cotSA→ytxO

2025-04-16 17:46:32

ghost

80

20d9a27a9e2740a4c93d545613875e210897ea30

96B3FFBC6FF2DFF1638E44F6FFFC46E18D212318

Biological materials
Mutant
BKE30900 (ΔcotS::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTGGTACACTCTGTTCACCC,  downstream forward: _UP4_AAAGCGTATCGGGAGGCGAA
BKK30900 (ΔcotS::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTGGTACACTCTGTTCACCC,  downstream forward: _UP4_AAAGCGTATCGGGAGGCGAA
References
Reviews
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Original Publications
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DC99E507696A1CB23140A1CBA45DA07D1F7C7D53

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Time of last update: 2025-04-21 02:40:40

Author of last update: Melvin.boenninger