azlC

azlC
168

amino acid exporter (with AzlD)

Locus
BSU_26710
Molecular weight
28.22 kDa
Isoelectric point
9.73
Protein length
254 aaSequenceBlast
Gene length
765 bpSequenceBlast
Function
export of amino acids
Product
component of amino acid exporter (with AzlD)
Essential
no
Synonyms
azlC, yrdH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1296 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,728,976 → 2,729,740
The protein
Catalyzed reaction/ biological activity
export of some branched-chain amino acids, histidine, and asparagine as well as 2,3-diaminopropionic acid (in complex with AzlD) PubMed
Protein family
azlC family (single member, according to UniProt)
Structure
O07942 (AlphaFold)
Localization
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
azlB-azlC-azlD-brnQ-yrdK
Description
PubMed
Regulation
repressed by AzlB PubMed
Regulatory mechanism
AzlB: repression, PubMed, in azlB regulon
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azlB→yrdK

2025-04-04 08:04:42

Jstuelk

105

CE7A54721725B20F53C4F64C9153F7B05416307A

77D75B92D3B22CF1350DD9E108E868095EE55DEB

Biological materials
Mutant
GP3601 (ΔazlB-azlC-azlD::kan) , available in Jörg Stülke's lab PubMed
GP3622 (ΔazlC-azlD::kan) , available in Jörg Stülke's lab PubMed
GP3623 (ΔazlB-azlC-azlD::spec) , available in Jörg Stülke's lab PubMed
BKE26710 (ΔazlC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAATCAACAACCTCCTACA,  downstream forward: _UP4_GTATGACGATGACTATGACG
BKK26710 (ΔazlC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAATCAACAACCTCCTACA,  downstream forward: _UP4_GTATGACGATGACTATGACG
References
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Time of last update: 2025-04-09 11:03:38

Author of last update: Jstuelk