epsM
168
UDP-2,4,6-trideoxy-2-acetamido-4-amino glucose acetyltransferase, extracellular polysaccharide synthesis
Locus
BSU_34240
Molecular weight
22.34 kDa
Isoelectric point
9.43
Function
Product
UDP-2,4,6-trideoxy-2-acetamido-4-amino glucose acetyltransferase
Essential
no
Synonyms
epsM, yvfD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0110 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,516,233 3,516,883
Phenotypes of a mutant
smooth colonies on MsGG medium, no biofilm formation PubMed
The protein
Catalyzed reaction/ biological activity
UDP-2,4,6-trideoxy-2-acetamido-4-amino glucose + acetyl-CoA --> UDP-2,4,6-trideoxy-2,4-diacetamido glucose (UDP-N,N'-diacetylbacillosamine) + CoA PubMed
Protein family
Transferase hexapeptide repeat family (according to UniProt)
coenzyme A PubMed
Structure
4M99 (PDB) (from Neisseria gonorrhoeae, 38% identity) PubMed
Expression and Regulation
Operons
Description
Regulation
Regulatory mechanism
EAR riboswitch: processive antitermination, in EAR riboswitch
Sigma factors
Additional information
Open in new tab
Biological materials
Mutant
MGNA-B609 (yvfD::erm), available at the NBRP B. subtilis, Japan
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
References
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Time of last update: 2025-01-24 18:43:35
Author of last update: Jstuelk