|
|
| (4 intermediate revisions by the same user not shown) |
| Line 1: |
Line 1: |
| − | =The PEP:Sugar Phosphotransferase System=
| + | #REDIRECT [[phosphotransferase systems]] |
| − | | |
| − | '''The PTS is a sugar transport system that couples the transport of a sugar to its phosphorylation. The phosphate group is derived from phosphoenolpyruvate (PEP) and transferred via the general PTS proteins [[ptsI|Enzyme I]] ([[ptsI|EI]]) and [[ptsH|HPr]] to the substrate-specific Enzymes II (EII) to the incoming sugars.'''
| |
| − | | |
| − | '''In addition to its role in sugar transport, the PTS is also involved in the regulation of carbon metabolism.'''
| |
| − | | |
| − | ==General PTS proteins==
| |
| − | * [[ptsI|Enzyme I]]
| |
| − | * [[ptsH|HPr]]
| |
| − | | |
| − | ==Sugar specific PTS proteins==
| |
| − | * [[PtsG]]: glucose permease, EIICBA
| |
| − | * [[GamP]]: glucosamine permease, EIICBA
| |
| − | * [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
| |
| − | * [[MtlA]], [[MtlF]]: mannitol permease
| |
| − | * [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease
| |
| − | * [[TreP]]: trehalose permease
| |
| − | * [[MalP]]: maltose permease
| |
| − | * [[FruA]]: fructose permease
| |
| − | * [[ManP]]: mannose permease
| |
| − | * [[YpqE]]: unknown EIIA component
| |
| − | * [[LevD]], [[LevE]], [[LevF]], [[LevG]]: fructose permease
| |
| − | * [[SacP]]: sucrose permease (high affinity)
| |
| − | * [[SacY]]: sucrose permease (low affinity)
| |
| − | * [[LicA]], [[LicB]], [[LicC]]: lichenan permease
| |
| − | * [[BglP]]: ß-glucoside permease
| |
| − | * [[YyzE]]: unknown PTS protein
| |
| − | * [[MtlF]]
| |
| − | * [[YwbA]]: unknown EIIC component
| |
| − | | |
| − | ==Proteins closely related to the PTS==
| |
| − | * [[Crh]]: [[ptsH|HPr]]-like protein with exculsively regulatory functions (His-15 is not conserved
| |
| − | * [[HprK]]: [[ptsH|HPr]]-kinase, key factor for carbon catabolite repression
| |
| − | | |
| − | ==Non-PTS proteins controlled by PTS-dependent phosphorylation==
| |
| − | * [[PRD-containing transcription factors]]
| |
| − | * [[GlpK]]
| |
| − | | |
| − | ==The PTS in [[SubtiPathways|''Subti''Pathways]]==
| |
| − | * [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]
| |
| − | * [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]
| |
| − | | |
| − | ==Related Lists==
| |
| − | * [[PRD-containing transcription factors]]
| |
| − | * [[transport proteins]]
| |
| − | * [[trigger enzymes]]
| |
| − | | |
| − | ==Relevant Reviews==
| |
| − | <pubmed>17158705 9871918 9663674 10627040 </pubmed>
| |
