yukB

yukB
168

membrane FtsK/SpoIIIE-like ATPase, part of the type VII protein secretion system YukD-EssB-YukB-YueB-YueC

Locus
BSU_31875
Molecular weight
172.00 kDa
Isoelectric point
5.462
Protein length
1495 aaSequenceBlast
Gene length
4488 bpSequenceBlast
Function
export of YfjA, YukE, YxiB, YwqH PubMed
Product
membrane FtsK/SpoIIIE-like ATPase, part of the type VII protein secretion system
Essential
no
Synonyms
yukB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1674 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,269,914  3,274,401
Phenotypes of a mutant
loss of secretion of YukE PubMed
The protein
Catalyzed reaction/ biological activity
export of YfjA, YukE, YxiB, YwqH PubMed
secretion and delivery of LXG domain toxins PubMed
Protein family
EssC family (single member, according to UniProt)
Domains
2 FtsK domains (aa 661-858, aa 993-1177) (according to UniProt)
Structure
C0SPA7 (AlphaFold)
Localization
membrane (according to SwissProt) PubMed
cytoplasm (Homogeneous) PubMed
Expression and Regulation
Operons
Genes
yukE-yukD-essB-yukB-yueB-yueC-yueD
Description
PubMed
Regulation
expressed in the stationary phase PubMed
expression is reduced in motile cells as compared to non-motile cells PubMed
Regulatory mechanism
DegU: activation, DegU-P, PubMed, in degU regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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yukE→yueD

2025-04-06 06:18:45

Jstuelk

133

BB0E1B9684F16E121BAA022EF986B0285FB41FA7

CDC40F8A7006CF56CF9A6155897E8BD27FFEC7AA

Biological materials
Mutant
MGNA-A625 (yukB::erm), available at the NBRP B. subtilis, Japan
BKE31875 (yukB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAATGGCGAACCCCCTTAC,  downstream forward: _UP4_TCTGCTGAAAGGGAGAGTGC
BKK31875 (yukB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAATGGCGAACCCCCTTAC,  downstream forward: _UP4_TCTGCTGAAAGGGAGAGTGC
References
Reviews
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Original Publications
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6007664F3D979B4D8D4662C7F6E5CF2F489268E3

Page visits: 4386

Time of last update: 2025-04-21 22:05:54

Author of last update: Jstuelk