licA

licA
168

lichenan-specific permease of the phosphotransferase system, EIIA of the PTS

Locus
BSU_38570
Molecular weight
12.04 kDa
Isoelectric point
4.64
Protein length
110 aaSequenceBlast
Gene length
333 bpSequenceBlast
Function
lichenan uptake and phosphorylation
Product
lichenan-specific PTS, EIIA component
Essential
no
Synonyms
licA, celC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1447 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,959,841 → 3,960,173
The protein
Protein family
PTS permease, lactose family PubMed
Domains
PTS EIIA domain type-3 (aa 3-101) (according to UniProt)
Structure
3K1S (PDB) (IIA(Cel) from B. anthracis, 42% identity)
P46319 (AlphaFold)
Paralogous protein(s)
GmuA
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
licB-licC-licA-licH
Description
PubMed
Regulation
carbon catabolite repression (CcpA) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
LicR: activation, PubMed, in licR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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licB→licH

2025-04-03 15:38:14

ghost

93

71a5a6a29188848adbfdb06b462667b975c2c7f8

DF3BDC652C79EB094E8D2D2CE50175B714C16E84

Biological materials
Mutant
BKE38570 (ΔlicA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATTCACGCGATTCACTTCCT,  downstream forward: _UP4_ACCGAGCAAAGGGGAGCAAG
BKK38570 (ΔlicA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATTCACGCGATTCACTTCCT,  downstream forward: _UP4_ACCGAGCAAAGGGGAGCAAG
References
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Time of last update: 2025-04-09 08:44:13

Author of last update: Melvin.boenninger