bpr

bpr
168

bacillopeptidase F

Locus
BSU_15300
Molecular weight
154.34 kDa
Isoelectric point
4.98
Protein length
Gene length
Function
protein degradation
Product
bacillopeptidase F
Essential
no
Synonyms
bpr, bpf

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4412 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,599,283 → 1,603,584
The protein
Protein family
peptidase S8 family (according to UniProt)
Inhibitor I9 domain (aa 68-177) (according to UniProt)
Peptidase S8 domain (aa 200-512) (according to UniProt)
Structure
6PAK (PDB) (AprE, corresponds to aa 199 ... 507, 32% identity) PubMed
secreted (according to Swiss-Prot),  extracellular (signal peptide) PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
repressed by glucose (7.7-fold) PubMed
Regulatory mechanism
DegU: activation, DegU-P PubMed, in degU regulon
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bpr

2025-02-25 04:54:45

Bzhu

53

7173ec171325e3d409066fc8af606e8312c6d43b

0EF7FBDA6FC11BE4610EA5DE17247E508D5D58F8

Biological materials
Mutant
KO7 (ΔnprE  ΔaprE  Δepr  Δmpr  ΔnprB  Δvpr  Δbpr), available as BGSC 1A1133
BKE15300 (Δbpr::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTTTCATCCCCCTTTTTC,  downstream forward: _UP4_TAAGTGGAAAAAAAGCTGCC
BKK15300 (Δbpr::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTTTCATCCCCCTTTTTC,  downstream forward: _UP4_TAAGTGGAAAAAAAGCTGCC
References
Reviews
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Original Publications
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Page visits: 4510

Time of last update: 2025-02-26 03:41:14

Author of last update: Jstuelk