sr1

sr1
168

small regulatory RNA controlling AhrC and KinA expression, regulatory peptide

Locus
BSU_14629
Molecular weight
4.00 kDa
Isoelectric point
4
Function
control of arginine metabolism, glycolysis, and sporulation
Product
small regulatory RNA, regulatory peptide
Essential
no
Synonyms
ykzW, ykzW, sr1, SR1P
Outlinks
BsubCyc UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
1,534,120 → 1,534,239
RNA
Catalyzed reaction/ biological activity
hybridizes to ahrC and kinA mRNA and inhibits AhrC and KinA translation PubMed
Interactions
ahrC mRNA-sr1 RNA PubMed
kinA mRNA-sr1 RNA PubMed
CsrA-sr1 RNA to promote base pairing between the sr1 RNA and the ahrC mRNA and to control arginine metabolism PubMed
The peptide
Catalyzed reaction/ biological activity:
the peptide controls the stability of the ''cggR-gapA'' mRNA PubMed
Protein family
the peptide is conserved in bacilli
Interactions
GapA-Sr1 PubMed
Expression and Regulation
Operons
Genes
sr1
Description
PubMed
Regulation
Repressed in the presence of glucose by CcpN PubMed
Regulatory mechanism
CcpN: repression, in ccpN regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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sr1

2025-04-05 22:17:27

ghost

97

cdd456f4f9f38239a8bd6de828c368acd2ff9101

6108D4013417F4507B07624F8909708801FA3461

Biological materials
Mutant
168 ykzW::cat, available in Sabine Brantl's lab
GP2210 (''sr1::cat''), available in Jörg Stülke's lab
GP2215 (''sr1::aphA3''), available in Jörg Stülke's lab
GP2216 (''sr1::phleo''), available in Jörg Stülke's lab
BKE14629 (Δsr1::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTCTTATTCCCCATTTC,  downstream forward: _UP4_TAAAAAAAAGCATGCGGCTT
BKK14629 (Δsr1::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTCTTATTCCCCATTTC,  downstream forward: _UP4_TAAAAAAAAGCATGCGGCTT
Labs working on this gene/protein
Sabine Brantl, Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany homepage
References
Reviews
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Original Publications
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FC93BA60BD185DE5EF31D5605F0B8294EC2E8E5A

Page visits: 5046

Time of last update: 2025-04-05 18:31:25

Author of last update: Jstuelk