dusB2
168
minor tRNA-dihydrouridine synthase 2
Locus
BSU_08030
Molecular weight
36.83 kDa
Isoelectric point
5.38
Function
tRNA modification
Product
tRNA-dihydrouridine synthase 2
Essential
no
Synonyms
yfjN, dusC, dus2
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0042 (Galperin et al., 2021)
Gene
Coordinates
876,426 → 877,403
The protein
Catalyzed reaction/ biological activity
5,6-dihydrouridine in tRNA + NAD+ → uridine in tRNA + H+ + NADH PubMed
5,6-dihydrouridine in tRNA + NADP+ → uridine in tRNA + H+ + NADPH PubMed
Protein family
Dus family (with DusB1, according to UniProt)
FMN PubMed
Structure
3B0P (PDB) (from Thermus thermophilus, 24% identity, from aa 12 ... 263) PubMed
Paralogous protein(s)
Expression and Regulation
Operons
Biological materials
Mutant
MGNA-C277 (yfjN::erm), available at the NBRP B. subtilis, Japan
References
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Time of last update: 2025-01-27 00:56:34
Author of last update: Jstuelk