sleB

sleB
168

spore cortex-lytic enzyme, putative cell wall hydrolase (N-acetylglucosamidase)

Locus
BSU_22930
Molecular weight
33.85 kDa
Isoelectric point
9.51
Protein length
305 aaSequenceBlast
Gene length
918 bpSequenceBlast
Function
degration of the spore cortex, germination
Product
spore cortex-lytic enzyme
Essential
no
Synonyms
sleB, ypeA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3773 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,399,152  2,400,069
The protein
Protein family
sleB family (single member, according to UniProt)
Domains
contains a signal peptide PubMed
Structure
4FET (PDB) (from B. anthracis, 50% identity) PubMed
P50739 (AlphaFold)
Localization
outer surface of the inner spore membrane PubMed
Expression and Regulation
Operons
Genes
sleB-ypeB
Description
PubMed
Regulation
expressed late during sporulation in the forespore (SigG) PubMed
Sigma factors
SigG: sigma factor, PubMed, in sigG regulon
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sleB→ypeB

2025-04-02 05:33:45

ghost

78

5d74caf239944fb1e30c0e6238601bcbb30b2316

2938A80B9758C9FA23B7F1A8D1FA5325A1915AE5

Biological materials
Mutant
MGNA-A399 (sleB::erm), available at the NBRP B. subtilis, Japan
1G21 ( sleB::spec), PubMed, available at BGSC
BKE22930 (sleB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTTTTCAAGCCTCCTAC,  downstream forward: _UP4_TAGCAGATATGAGAAAGCAT
BKK22930 (sleB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTTTTCAAGCCTCCTAC,  downstream forward: _UP4_TAGCAGATATGAGAAAGCAT
References
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Page visits: 6037

Time of last update: 2025-04-22 17:45:53

Author of last update: Jstuelk