Difference between revisions of "PfkA"
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| − | * '''Description:''' | + | * '''Description:''' is the main controling enzyme of the glycolysis. <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Product''' || 6-phosphofructokinase | |style="background:#ABCDEF;" align="center"| '''Product''' || 6-phosphofructokinase | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || phosphorylation of fructose 6-phosphat |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34,1 kDa, 6.14 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34,1 kDa, 6.14 | ||
Revision as of 16:19, 7 January 2009
- Description: is the main controling enzyme of the glycolysis.
| Gene name | pfkA |
| Synonyms | pfk |
| Essential | yes |
| Product | 6-phosphofructokinase |
| Function | phosphorylation of fructose 6-phosphat |
| MW, pI | 34,1 kDa, 6.14 |
| Gene length, protein length | 957 bp, 319 amino acids |
| Immediate neighbours | accA, pyk |
| Gene sequence (+200bp) | Protein sequence |
| Genetic context File:GenE context.gif | |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate
- Protein family: phosphofructokinase family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- 3 x nucleotide binding domain (ATP) (21–25), (154–158), (171–187)
- Modification:
- Cofactor(s): ATP
- Effectors of protein activity:
- Interactions:
- Localization: Cytoplasm
Database entries
- Structure:
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
