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| − | * '''Description:''' oligopeptide ABC transporter (peptide-binding protein) <br/><br/>
| + | #REDIRECT[[appA/1]] |
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| − | {| align="right" border="1" cellpadding="2"
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| − | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| − | |''appA''
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| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || oligopeptide ABC transporter (peptide-binding protein))
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || uptake of oligopeptides
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| − | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 61 kDa, 5.733
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| − | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1629 bp, 543 aa
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| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[appF]]'', ''[[appB]]''
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| − | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/appA_nucleotide.txt Gene sequence (+200bp) ]'''
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| − | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/appA_protein.txt Protein sequence]'''
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| − | |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors
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| − | |colspan="2" | '''Genetic context''' <br/> [[Image:appA_context.gif]]
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| − | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| − | |}
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| − | __TOC__
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| − | <br/><br/><br/>
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| − | =The gene=
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| − | === Basic information ===
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| − | * '''Locus tag:'''
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| − | ===Phenotypes of a mutant ===
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| − | === Database entries ===
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| − | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/appDFABC.html]
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| − | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11087]
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| − | === Additional information===
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| − | =The protein=
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| − | === Basic information/ Evolution ===
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| − | * '''Catalyzed reaction/ biological activity:'''
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| − | * '''Protein family:''' bacterial solute-binding protein 5 family (according to Swiss-Prot)
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| − | * '''Paralogous protein(s):'''
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| − | === Extended information on the protein ===
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| − | * '''Kinetic information:'''
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| − | * '''Domains:'''
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| − | * '''Modification:'''
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| − | * '''Cofactor(s):'''
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| − | * '''Effectors of protein activity:'''
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| − | * '''Interactions:'''
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| − | * '''Localization:''' cell membrane (according to Swiss-Prot)
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| − | === Database entries ===
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| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1XOC 1XOC] (complex with nonapeptide)
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| − | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P42061 P42061]
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| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU11380 BSU11380]
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| − | * '''E.C. number:'''
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| − | === Additional information===
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| − | =Expression and regulation=
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| − | * '''Operon:''' ''[[appD]]-[[appF]]-[[appA]]-[[appB]]-[[appC]]''
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| − | * '''[[Sigma factor]]:'''
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| − | * '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed], repressed by [[CodY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
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| − | * '''Regulatory mechanism:''' [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
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| − | * '''Additional information:'''
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| − | =Biological materials =
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| − | * '''Mutant:'''
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| − | * '''Expression vector:'''
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| − | * '''lacZ fusion:'''
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| − | * '''GFP fusion:'''
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| − | * '''two-hybrid system:'''
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| − | * '''Antibody:'''
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| − | =Labs working on this gene/protein=
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| − | [[Tony Wilkinson]], York University, U.K. [http://www.york.ac.uk/depts/chem/staff/ajw.html homepage]
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| − | =Your additional remarks=
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| − | =References=
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| − | # Mäder et al. (2002) Transcriptome and Proteome Analysis of ''Bacillus subtilis'' Gene Expression Modulated by Amino Acid Availability. ''J. Bacteriol'' '''184:''' 1844288-4295 [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]
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| − | # Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
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