Difference between revisions of "T-box"
(→Genes controled by T-box element) |
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| − | The T-box element is | + | The T-box element is ann [[RNA switch]] that controls genes involved in amino acid metabolism. |
In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid. | In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid. | ||
| Line 7: | Line 7: | ||
* Induction by cysteine limitation | * Induction by cysteine limitation | ||
| − | ** [[cysE]]-[[cysS]]-[[mrnC]]-[[yacO]]-[[yacP]]'' | + | ** ''[[cysE]]-[[cysS]]-[[mrnC]]-[[yacO]]-[[yacP]]'' |
* Induction by tryptophan limitation | * Induction by tryptophan limitation | ||
** ''[[rtpA]]-[[ycbK]]'' | ** ''[[rtpA]]-[[ycbK]]'' | ||
Revision as of 19:47, 27 May 2009
The T-box element is ann RNA switch that controls genes involved in amino acid metabolism.
In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.
Genes controlled by T-box elements
- Induction by cysteine limitation
- Induction by tryptophan limitation
