Difference between revisions of "MntD"

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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[mntA]]-[[mntB]]-[[mntC]]-[[mntD]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed]
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
* '''Regulation:'''  
+
* '''Regulation:''' repressed by Mn(2+) ([[MntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed]
  
* '''Regulatory mechanism:'''  
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* '''Regulatory mechanism:''' MntR: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed]
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=Labs working on this gene/protein=
 
=Labs working on this gene/protein=
 +
 +
[[John Helmann]], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
  
 
=Your additional remarks=
 
=Your additional remarks=

Revision as of 09:56, 24 May 2009

  • Description: manganese ABC transporter

Gene name mntD
Synonyms ytgD
Essential no
Product manganese ABC transporter
Function manganese uptake
MW, pI 30 kDa, 6.308
Gene length, protein length 885 bp, 295 aa
Immediate neighbours ythC, mntC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MntD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ABC-3 integral membrane protein family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism: MntR: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References

  1. Que Q, Helmann JD. (2000) Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins. Mol Microbiol. Mar;35(6): 1454-68. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed