PyrF

• Description: orotidine 5'-phosphate decarboxylase
  
  

Gene name	pyrF
Synonyms
Essential	no
Product	orotidine-5'-phosphate decarboxylase
Function	pyrimidine biosynthesis
MW, pI	25 kDa, 5.835
Gene length, protein length	717 bp, 239 aa
Immediate neighbours	pyrD, pyrE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Orotidine 5'-phosphate = UMP + CO₂ (according to Swiss-Prot)

• Protein family: Type 1 subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1DBT

• Swiss prot entry: P25971

• KEGG entry: BSU15550

• E.C. number: 4.1.1.23

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed