Difference between revisions of "GltC"
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(→Expression and Regulation) |
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=Expression and Regulation= | =Expression and Regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' gltC [http://dbtbs.hgc.jp/COG/prom/gltC.html] |
| − | * '''Sigma factor:''' | + | * '''Sigma factor:''' SigA [http://dbtbs.hgc.jp/COG/prom/gltC.html] |
| − | * '''Regulation:''' | + | * '''Regulation:''' autoregulation by GltC [http://dbtbs.hgc.jp/COG/prom/gltC.html] |
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' autorepression |
=Biological Materials = | =Biological Materials = | ||
Revision as of 18:49, 10 December 2008
- Synonyms:
- Description: Transcriptional activator of the gltAB operon. Activates expression of the operon in the absence of arginine.
Contents
The gene
Basic information
- Coordinates:
- Gene length:
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of the gltAB operon
- Protein family: LysR-type transcription regulator
- Paralogous protein(s): none, but there are 19 members of the LysR family in B. subtilis
Database entries
- Structure
- Swiss prot entry
- KEGG entry
Extended information on the protein
- Kinetic information
- Domains DNA-binding helix-turn-helix motif: AA 18 ... 37
- Modification
- Effectors of protein activity:2-oxoglutarate
- Interactions:
- Localization
Expression and Regulation
- Operon: gltC [3]
- Sigma factor: SigA [4]
- Regulation: autoregulation by GltC [5]
- Regulatory mechanism: autorepression
Biological Materials
- Mutant:, Expression vector
- Expression vector:
- lacZ fusion:
- GFP fusion:
- Antibody: available in Stülke lab
Phenotypes of a Mutant
Additional remarks
- Labs working on this gene/protein:
Linc Sonenshein, Tufts University, Boston, MA, USA [6]
Jörg Stülke, University of Göttingen, Germany [7]
