Difference between revisions of "Sandbox"

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* '''Description:''' pantetheine-phosphate adenylyltransferase <br/><br/>
+
* '''Description:''' 2-dehydropantoate 2-reductase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ylbI''
+
|''ylbQ''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''coaD''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || pantetheine-phosphate adenylyltransferase
+
|style="background:#ABCDEF;" align="center"| '''Product''' || 2-dehydropantoate 2-reductase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || lipopolysaccharide biosynthesis
+
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of coenzyme A
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 5.652  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.857  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 483 bp, 161 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 894 bp, 298 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylbH]]'', ''[[ylbJ]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylbP]]'', ''[[yllA]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13375&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13384&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:ylbI_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:ylbQ_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
Line 29: Line 29:
 
__TOC__
 
__TOC__
  
<br/><br/>
+
<br/><br/><br/>
  
 
=The gene=
 
=The gene=
Line 43: Line 43:
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13361]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13369]
  
 
=== Additional information===
 
=== Additional information===
Line 54: Line 54:
 
* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' bacterial coaD family (according to Swiss-Prot)
+
* '''Protein family:''' ketopantoate reductase family (according to Swiss-Prot)
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
Line 76: Line 76:
 
=== Database entries ===
 
=== Database entries ===
  
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1O6B 1O6B] (complex with ADP)
+
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3LGO 3LGO]
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34797 O34797]
+
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34661 O34661]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15020]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15110]
  
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.7.3 2.7.7.3]
+
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.169 1.1.1.169]
  
 
=== Additional information===
 
=== Additional information===

Revision as of 22:56, 11 May 2009

  • Description: 2-dehydropantoate 2-reductase

Gene name ylbQ
Synonyms
Essential no
Product 2-dehydropantoate 2-reductase
Function biosynthesis of coenzyme A
MW, pI 33 kDa, 5.857
Gene length, protein length 894 bp, 298 aa
Immediate neighbours ylbP, yllA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YlbQ context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ketopantoate reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed